| |
|
|
Monoclonal VEGF-C antibody |
VEGF-C has long N and C terminal propeptide extensions. The VEGF-C propeptide undergoes stepwise proteolytic processing to generate lignands that bind to VEGF-R3/R2, which is involved in lymphangiogenesis and tumor growth and metastasis of several cancers. The predicated molecular weight is 15.5 KDa. Entrez Gene IDs: 7422 (Human)
|
More Info
|
|
|
| |
|
|
Monoclonal TGF-¦Â1 antibody |
TGF-¦Â1 was first identified in human platelets as a protein with a molecular mass of 25 kilodaltons with a potential role in wound healing. It was characterized as a large protein precursor (containing 390 amino acids) that was proteolytically processed to produce a mature peptide of 112 amino acids. Entrez Gene IDs: 7040 (Human)
|
More Info
|
|
|
| |
|
|
Monoclonal Human Prostate specific antigen (PSA) antibody |
Kallikrein 3, also known as prostate specific antigen (PSA), is a serine protease of the human tissue Kallikrein gene family. PSA is secreted into the seminal plasma in high concentrations. A small portion of PSA ¡°leaks¡± into the systemic circulation, which is increased from prostate cancer tissue than normal prostate tissue. PSA is a well-established tumor marker that aids the diagnosis, staging, and follows up of prostate cancer.
|
More Info
|
|
|
| |
|
|
Monoclonal NT-proBNP antibody |
The N-terminal prohormone of brain natriuretic peptide (NT-proBNP) is a 76 amino acid N-terminal protein that is cleaved to release brain natriuretic peptide.
|
More Info
|
|
|
| |
|
|
Monoclonal NSE antibody |
Enolase (2-phospho-D-glycerate hydrolase) is a cytoplasmic enzyme that is involved in the glycolytic pathway, in which it converts 2-phosphoglycerate to phosphoenolpyruvate. Elevated serum levels of Enolase 2 are commonly found among a variety of conditions associated with central nervous system damage such as stroke, traumatic brain injury, multiple sclerosis, and Alzheimer¡¯s disease and In malignant tumors of neuroendocrine origin, such as small cell lung cancer, APUDoma, and neuroblastoma.
|
More Info
|
|
|
| |
|
|
Monoclonal myoglobin antibody |
The myoglobin is a cardiac marker used to assist diagnoses of an acute myocardial injury. It is a single-chain globular protein of 153 amino acids, containing a heme prosthetic group in the center, which is the primary oxygen-carrying pigment of muscle tissues.
|
More Info
|
|
|
| |
|
|
Monoclonal MUC-1 antibody |
This gene encodes a membrane-bound protein that is a member of the mucin family. CA15-3 (Cancer Antigen 15-3) is a tumor marker used to monitor certain cancers, especially breast cancer. It is found on the surface of many types of cancer cells and shed into the blood stream. Entrez Gene IDs: 4582 (Human)
|
More Info
|
|
|
| |
|
|
Monoclonal LDL-R antibody |
The low density lipoprotein receptor (LDL-R) is the founding member of the LDL-R family of widely expressed cell surface scavenger receptors. Hepatocyte LDL-R is responsible for endocytosis and clearing of most plasma LDL cholesterol. The predicated molecular weight is 85.6 KDa & 66.8 KDa. Entrez Gene IDs: 7422 (Human)
|
More Info
|
|
|
| |
|
|
Monoclonal IGFBP-4 antibody |
Insulin like growth factor binding protein 4 (IGFBP4) is a member of the IGFBP4 family, which is a secreted glycoprotein that maintain IGFI and IGFII in the circulation and direct them to their target tissues. Human IGFBP4 was isolated from human plasma based on its ability to bind immobilized IGFI. Human IGFBP4 cDNA encodes a 258 amino acid (aa) residue precursor protein with a predicted 21 aa residue signal peptide that is processed to generate the 237 aa residue mature human IGFBP4. IGFBP4 involved in glucose metabolism by inhibit IGF actions by binding to IGFs and preventing the binding of IGFs to IGF receptors.
|
More Info
|
|
|
| |
|
|
Monoclonal IGF-1 antibody |
Insulin-like growth factor I (IGF-1) is a ubiquitous polypeptide synthesized by virtually all cells of the body. It is a 70 amino acid protein. It is involved in glucose metabolism.
|
More Info
|
|
|
| |
|
|
Monoclonal H-FABP antibody |
Heart-type Fatty Acid-Binding Protein (H-FABP) is a cardiac marker used to assist diagnoses of an acute myocardial injury. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode.
|
More Info
|
|
|
| |
|
|
Monoclonal D-dimer antibody |
D-dimer is a fibrin degradation product (DFP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It contains two cross-linked D fragments of the fibrin protein. D-dimer concentration may be useful to help diagnose thrombosis.
|
More Info
|
|
|
